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The Food and Drug Administration (FDA)-approved iron supplement ferumoxytol, which contains iron oxide nanoparticles, can suppress growth of early mammary cancers and lung cancer metastasis by inducing pro-inflammatory M1 type macrophage polarization in the tumour tissue, offering a new ‘off label’ application for an approved drug.
Investigation of the electronic structure in few-layer phosphorene reveals optical transitions relevant for technologically important electronic and optoelectronic applications.
Multi-terminal superconducting Josephson junctions are used to induce topologically protected transitions between gapless and gapped states, showing the potential for creating artificial topological materials.
The precise characterization of magnetic fields with a bandwidth of up to 3 GHz and localized on a nanometric scale is achieved by means of the coherent control of single electron and nuclear spins.
Pair correlation microscopy is used to show that the shape of a nanoparticle can affect the way it crosses various barriers inside a cell, and this ultimately determines the site at which the nanoparticle releases its drug payload.
Spatially resolved measurements of the absorption, internal quantum efficiency and photoluminescence quantum yield of InP single nanowire solar cells allow the determination of intrinsic losses and thermodynamic limits of these nanophotonic devices.
A Josephson junction with a weak link made of the quantum spin Hall insulator HgTe shows evidence of topological superconductivity in response to an a.c. excitation.
The phenomenon of circumferential faceting in multiwalled nanotubes of general chirality and identity is rationalized in terms of interwall registry patterns between adjacent layers of curved hexagonal lattices.
Quantum dots encapsulated inside DNA icosahedra that display a single endocytic ligand are used to track compartmental dynamics along endocytic pathways.
Solid-state nanopores can be used to directly observe individual knots in linear and circular DNA molecules of arbitrary length, and to determine the knot's size, position, and probability of occurrence as a function of DNA length.
Few-layered, vertically aligned MoS2 films can efficiently harvest visible light for photocatalytic water disinfection, allowing >99.999% bacteria to be rapidly inactivated.
Magnetotactic bacteria that respond to oxygen gradients can be used to carry drug payloads deep into the hypoxic regions of tumours, offering a way to improve the therapeutic index of various nanocarriers.
Single-crystal graphene can be grown on a copper foil at a rate of 60 μm s-1 by using an adjacent oxide substrate that continuously supplies oxygen to the surface of the copper catalyst.
Individual ion qubits held in a planar ion trap are optically addressed with scalable nanophotonic waveguides and focusing grating couplers integrated with the trap chip.
Synthetic nanoparticles containing rapamycin — a common immunosuppressant drug — when co-administered with any free antigen can induce immune tolerance, offering a way to rescue novel drugs that have failed in the clinic due to antidrug antibodies.
Lateral displacement pillar arrays can now be used to separate nanoscale colloids including exosomes, offering new opportunities for on-chip sorting and quantification of biocolloids by size.