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A method for overcoming antibiotic resistance uses multimodal nanoparticles that target bacterial defence mechanisms while enhancing the innate immune response.
A double-blind, randomized, controlled human exposure trial of highly purified and thin nanometre-sized graphene oxide nanosheets shows that acute inhalation of aerosolized nanoparticles is not associated with harmful effects in healthy humans.
How can light be efficiently manipulated below the single-pixel level? An answer is now provided using near-field interactions for nanopillars in a metasurface — phase gradients in the gaps between the nanopillars constitute a new degree of freedom that enables efficient wavefront control at the nanoscale.
Robotics and machine learning are combined to predict and prepare a variety of nanocomposite materials with properties mimicking those of various types of plastics, starting from natural building blocks.
A genetically engineered variant of the stimulator of interferon genes (STING) protein is delivered to cancer cells, showing potential for clinical impact.
A distance-based mapping strategy using single-molecule fluorescence resonance energy transfer via DNA eXchange (FRET X) enables full-length fingerprinting of intact protein sequences.
The performance of three-terminal molecular transistors is enhanced through the harnessing of quantum interference in the edges of graphene electrodes.
By confining and concentrating light in a nanometric volume at the apex of a metallic tip, sub-molecule-scale control of a basic photochemical reaction — phototautomerization — is now shown to be possible. Applicable to other photo-induced reactions, this technique signals a new strategy for the synthesis of complex molecules on surfaces.
A process that leverages capillary interactions between oligomers in an elastomeric polydimethylsiloxane substrate and deposited Ga enables the formation of Ga nanodroplets with nanoscale gaps in a single step. Gap-plasmon resonances excited within the nanogaps give rise to structural colours that can be tuned by changing the oligomer content in the substrate or by mechanical stretching.
An aptamer-based nanobiosensor has been integrated into a wearable sweat sensor, allowing non-invasive tracking of the female reproductive hormone, oestradiol, with the potential to deliver sustainable solutions to female reproductive healthcare needs.
An encodable DNA clutch with the ability to recognize microenvironmental molecular inputs intelligently complements the remote control of a 200-nm sized magnetic nanomachine. This nanomachine interacts with biological machinery in vitro when the encoded clutch selectively engages the engine with the rotor while external magnetic fields power the rotation.
A robust initialization protocol has been demonstrated for a four-qubit nuclear spin register in silicon. The protocol, driven electrically through electric-dipole spin resonance, enables high-fidelity qubit control and hence a route to a register-based quantum computer that exploits the exceptional coherence properties of atom qubits in silicon.
This Review highlights the current understanding of mechanisms underlying the mechanical changes occurring in diseased and immune cells and discusses new approaches to leverage and target biomechanical cues for immune engineering at various length scales for therapeutic interventions.
Pre-adsorption of water molecules on a material surface, followed by assembly of a van der Waals (vdW) structure, provides a vdW water gap with a height that can be precisely tuned through variation of the amount of water adsorbed at the interface. This approach is applicable to different two-dimensional and even three-dimensional homo- and heterojunctions.
The Review discusses the state-of-the-art polymer nanocomposites from three key aspects: dipole activity, breakdown resistance and heat tolerance for capacitive energy storage applications.
Chitosan/glucose co-polymers encapsulating silver sulfide quantum dots can be used to improve oral delivery of insulin in different animal models without hypoglycaemic incidents.
