Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain
the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in
Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles
and JavaScript.
Researchers observe that cells of the post-implantation mouse epiblast can revert to an embryonic stem cell–like state without the addition of exogenous genes.
Two methods enable the drawing of genome-wide chromatin interaction maps: one looks at protein-independent folding principles, the other at protein-mediated functional interactions.
Certain yeast previously assumed to lack RNA interference machinery instead have alternative enzyme variants, which can in turn be transplanted to truly deficient species.
The development of leader sequences that stimulate mRNA translation in a species-independent manner could offer new possibilities for eukaryotic protein production and proteomic research.
Visualization of choline-containing phospholipids in cells and in vivo is made possible by the metabolic incorporation of a choline analog with an alkyne handle for click chemistry–based labeling.
By fusing a light-sensitive domain of an oat plant protein to Rac1, researchers created a genetically encoded protein fusion that can be reversibly activated with blue light and control cell movement—an attractive alternative to current caging tools.