Researchers observe that cells of the post-implantation mouse epiblast can revert to an embryonic stem cell–like state without the addition of exogenous genes.
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References
Bao, S. et al. Epigenetic reversion of post-implantation epiblast to pluripotent embryonic stem cells. Nature 461, 1292–1295 (2009).
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de Souza, N. Many routes to pluripotency. Nat Methods 6, 864–865 (2009). https://doi.org/10.1038/nmeth1209-864a
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DOI: https://doi.org/10.1038/nmeth1209-864a
