By monitoring the size-dependence of particle distribution in the lamellipodium, fluid flow in moving cells can be measured.
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References
Keren, K. et al. Intracellular fluid flow in rapidly moving cells. Nat. Cell Biol. 11, 1219–1224 (2009).
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de Souza, N. A fluid situation. Nat Methods 6, 790–791 (2009). https://doi.org/10.1038/nmeth1109-790a
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DOI: https://doi.org/10.1038/nmeth1109-790a