Dietary restriction and health
- Submission status
- Open
- Submission deadline
Limiting food consumption, or the timing of food consumption, has been shown to have beneficial effects across a wide range of species, including yeast, worms, flies, rodents, non-human primates, and humans. Approaches to dietary restriction include the limitation of total caloric intake; the limitation of specific nutrients, particularly protein or select amino acids; or the temporal restriction of food intake, also known as intermittent fasting. In mammals, dietary restriction can increase healthspan and lifespan by protecting against ageing-related disorders such as cancer, neurodegenerative, cardiovascular, and metabolic diseases, and inflammation. The mechanisms underlying such effects include reduced insulin/IGF1 and mTORC1 signaling, reduced protein synthesis, reduced oxidative stress, and the activation of geroprotective sirtuins. Individuals can vary widely in their responses to various dietary restriction regimens, however, posing a challenge for translating these approaches to the clinic.
This Collection welcomes original research on all aspects of dietary restriction, including the molecular pathways involved, the resulting health outcomes, and the factors affecting its efficacy.
This Collection supports and amplifies research related to SDG 3.
Editors
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Yongting Luo, PhD
Department of Nutrition and Health, China Agricultural University, Beijing, China
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Edyta Łuszczki, PhD
Medical College of Rzeszów University, Rzeszów, Poland
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Antonio Paoli, MD
Department of Biomedical Sciences, University of Padua, Padua, Italy
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Mikiko Watanabe, MD, PhD
Sapienza University, Rome, Italy
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Falak Zeb, PhD
University of Sharjah, Sharjah, UAE
Yongting Luo, PhD, Department of Nutrition and Health, China Agricultural University, Beijing, China
Yongting Luo is an Associate Professor at the Department of Nutrition and Health, China Agricultural University. His research interests include the basic vascular biology, the pathogenesis and targeted interventions of cardiovascular diseases. Dr. Luo has been an Editorial Board Member for Scientific Reports since 2024.
Edyta Łuszczki, PhD, Medical College of Rzeszów University, Rzeszów, Poland
Edyta Łuszczki is an Assistant Professor / Lecturer at the Institute of Health Sciences of the Medical College of the University of Rzeszów and the head of the Human Nutrition Laboratory. She is a vice-president of European Childhood Obesity Group (ECOG). In her scientific work, she implemented the scope of research on the topic of nutrition for children and adolescents. She is the author and co-author of 75 scientific publications with a total impact factor score of 538.870. She is involved in many scientific projects on child and adolescent nutrition. Dr. Łuszczki has been an Editorial Board Member for Scientific Reports since 2023.
Antonio Paoli, MD, Department of Biomedical Sciences, University of Padua, Padua, Italy
Antonio Paoli is full professor of Exercise and Sports Sciences and Director of the Nutrition & Exercise Physiology Laboratory of the Department of Biomedical Sciences, University of Padua, Italy. He is also Director and Professor of Strength Training and Sport Nutrition at the University UCAM (Murcia, Spain) and Head of Human Health Laboratory Lobachevsky University - Niznij Novgorod - Russia. From 2021 he holds the position of Vice Rector for Wellness and Sport at the University of Padua. His research interests include ketogenic diet and fasting, the interaction between exercise and diet and the molecular bases of exercise training adaptation. Dr. Paoli has been an Editorial Board Member for Scientific Reports since 2022.
Mikiko Watanabe, MD, PhD, Sapienza University, Rome, Italy
Dr. Watanabe serves as a Research Fellow at Sapienza University in Rome, where she specializes in obesity research, with a focus on nutritional ketosis. Dr. Watanabe has been an Editorial Board Member for Scientific Reports since 2024.
Falak Zeb, PhD, University of Sharjah, Sharjah, UAE
Falak Zeb is working as Research Associate at Research Institute for Medical and Health Sciences, University of Sharjah, UAE. His research interest include intermittent fasting, circadian rhythm, gut microbiota, molecular and clinical nutrition, phytonutrients and its impact on gut microbiota. He has been serving as an Editorial Board Member of Scientific Reports. Dr. Zeb has been an Editorial Board Member for Scientific Reports since 2024.
