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The targeted delivery of multicomponent cargos to cancer cells by nanoporous particle-supported lipid bilayers
A nanocarrier—synthesized by the fusion of liposomes to spherical, nanoporous silica particles and subsequent modification of the lipid bilayer with targeting peptides and fusogenic peptides—shows the targeted delivery and controlled release of chemically diverse multicomponent cargos within the cytosol of certain cancer cells.
- Carlee E. Ashley
- , Eric C. Carnes
- & C. Jeffrey Brinker
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News & Views |
Particles release
By using drug-encapsulating nanoparticles as the basis for electrostatic assembly, it is possible to generate highly functional films that do double duty. These adaptable thin films can be used both for releasing the drug in a controlled fashion and for biological imaging.
- Paula T. Hammond