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This study uncovers the role of aromatic clusters in the receptor extracellular loop of sialic-acid-binding immunoglobulin-like lectins that recognize carbon nanotubes and suggests inhibiting Syk signalling as a therapeutic intervention against inflammation.
Sonogenetics provides neuron-specific activation at high spatiotemporal resolution ex vivo in retina and in vivo deep in the visual cortex using the AAV gene delivery of a mechanosensitive ion channel and low-intensity ultrasound stimulations.
Ionic flow through ångström-scale channels facilitates selectivity beyond steric effects between ions of same charge and hydrated diameter. Here, with two-dimensional channels, the authors show that ion position in the channel influences selectivity.
Sensory signal attributes can be disentangled exploiting the computation-in-superposition capability of hyperdimensional computing, in-memory computing and associated intrinsic device-level stochasticity.
The crystallization of nanoparticles is observed with single-particle resolution via electron microscopy. The growth modes are explained via computer simulations, unifying the understanding of crystallization from the atomic to micrometre scale.
Approaches to treat inflammatory bowel disease with probiotics or artificial enzymes have advantages and limitations. Here we combine the advantages to overcome the individual limitations by modifying probiotics with artificial enzymes and demonstrate application in treating inflammatory bowel disease.
A simple descriptor called degree-of-isolation is proposed to describe the microenvironment and determine the effectiveness of active sites in single-site alloys. For a single-site alloy with a high degree-of-isolation, alternation of the active centre strongly affects the selectivity.
The authors use a DNA-framework-based molecular classifier to perform biomarker panel screening and analyse six biomarkers across three-dimensional datatypes to obtain a molecular taxonomy for prostate cancer diagnosis.
In multilayer WSe2, dipolar excitons with Coulomb-bound electron and hole pairs located in every other layer show unique valleytronic superlattice structure and electrical tunability.
Superconducting single-photon detectors are critical for quantum communication, fluorescence lifetime imaging and remote sensing, but commonly operate at very low temperatures. Now, high-temperature cuprate superconducting nanowires enable single-photon detection up to 25 K.
Differential phase contrast scanning transmission electron microscopy probes the electric field distribution across a GaN-based semiconductor heterointerface.
A semirigid stamp and a standard photolithography mask-aligner enable a reliable and scalable pickup and release process for van der Waals materials integration at the wafer scale.
Multiple alternating layers of two-dimensional materials and epilayers are grown on III–N and III–V substrates in a single growth run. Then, each epilayer is harvested by mechanical exfoliation, producing multiple freestanding membranes from a single wafer.
By integrating split ferroelectric capacitors with complementary characteristics in the same memory cell, this architecture tackles the problem of conflicting memory requirements for training and inference, which has long plagued edge intelligence applications.
A flash memory device fabricated with atomically sharp van der Waals heterostructures shows a programming speed of 20–30 ns and power consumption in the nanowatt region.