Collections

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    Non-adherence to antihypertensive medications is very common among the hypertensive community and an important contributor to the phenomenon of apparent resistance to treatment. This group of articles focuses on its prevalence, determinants, detection and suggested approaches to management.

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    Arterial stiffness has long been known to predict development of cardiovascular events and is a major determinant of central blood pressure, which prognosticates for cardiovascular outcomes independently of, and possibly with greater predictive power than, brachial blood pressure. This collection of articles focuses in new findings related to the measurement of these parameters and their association with a variety of endpoints in different ethnic groups.

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    This article collection focuses on mineralocorticoids in human hypertension. Mineralocorticoids’ importance in blood pressure regulation is highlighted by altered mineralocorticoid activity--or simulacra of altered mineralocorticoid activity--in monogenic disorders of hypertension. Primary aldosteronism is the most common form of secondary hypertension and this condition of inappropriate mineralocorticoid secretion is present in approximately 20% of patients with resistant hypertension.

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    The Academic Journal portfolio recently published a Precision Medicine campaign, in which our Editors selected over 50 articles across a range of specialities which they believe contribute to the advancement of research in this area. In light of this the Journal of Human Hypertension is pleased to showcase more research that the journal has published on this increasingly interesting and evolving field of medicine, the potential of which can transform the care and treatment of individuals globally.

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    The diagnosis and treatment of hypertension is primarily based on blood pressure measure obtained in the clinic setting. However, there is extensive evidence that out-of-clinic blood pressure can differ substantially from clinic blood pressure. Out-of-clinic blood pressure has been deemed the "true" blood pressure as it represents the blood pressure that a person experiences in the naturalistic environment. There is increasing evidence that out-of-clinic blood pressure is more strongly associated with cardiovascular disease events and mortality compared to clinic blood pressure.

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    Hypertension is a cardiovascular disease risk factor of unquestionable importance, particularly for older adults. The number of adults aged 60 years or older is substantially increasing, and the prevalence of hypertension among older adults is exceedingly high. Not only is hypertension a major risk factor for cardiovascular events, it is also a cause of chronic renal failure and end-stage renal disease. Together these factors are further contributing to the growing chronic disease burden in older adults. As a result, hypertension among older adults is a public health concern.

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    Cardiovascular disease remains a leading cause of morbidity. Much research has been conducted to identify risk factors associated with incident cardiovascular disease onset and the underlying mechanisms linking these risk factors to cardiovascular disease. One of the most important risk factors is hypertension as it is common, contributes to a large cardiovascular disease burden, and is also modifiable.

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    Bringing together recent content selected by the editor from the Journal of Human Hypertension. This selection of topical content covers a range of topics including blood pressure monitoring, hypertension risk and therapy.