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A new study shows that, in mice, motile commensal bacteria are prevented from crossing the mucosal barrier by the TLR5-induced production of anti-flagellin antibodies, which both immobilize the bacteria and downregulate flagellar gene expression.
The UK Five Year Antimicrobial Resistance Strategy report calls for an integrated response from the academic, pharmaceutical and political sectors to combat antibiotic resistance.
A study in patients with rheumatoid arthritis shows a potential role of the gut bacteriumPrevotella copriin the development of this autoimmune disease.