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Deep brain stimulation is an effective treatment for obsessive–compulsive disorder but is rarely used. Action is needed by psychologists, psychiatrists and insurers so that patients with otherwise intractable cases can receive this therapy to improve their mental health.
The H3D Centre is a South African-based academic translational research unit that has had many successes and could provide a much-needed model for drug discovery and development in Africa.
The release of breast cancer cells into the circulation occurs mostly during rest — a surprising discovery that may help researchers to better study and target cancer metastasis.
Women are credited less than men are in scientific publications and patents; a study suggests that their contributions are systematically under-recognized across all career stages and scientific fields.
A new approach to pandemic and epidemic intelligence is needed that includes modern approaches to surveillance and risk assessment, as well as improved trust and cooperation between stakeholders and society.
Improved screening, novel therapies and a focus on health equity can reduce cancer mortality by 50% in the next 25 years, but these must be underpinned by an investment in basic, translational and clinical research, along with open data.
Patients with HER2-low metastatic breast cancer are a historically overlooked group, but a phase 3 trial reveals trastuzumab deruxtecan as a new treatment option that prolongs survival.
Online access during the pandemic widened participation in scientific conferences for women, young scientists and those from low- and middle-income countries, and should be continued
Leading researchers explain how the COVID-19 pandemic has spurred research on wearables, genomic surveillance, behavioral interventions and drug discovery.
In a first-in-human study, intranasal transplantation of mesenchymal stromal cells was safe and well-tolerated in newborns who had suffered a stroke — laying the foundation for large-scale clinical trials.