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The natural history of untreated Lyme arthritis is rarely observed as most cases are successfully treated with antibiotics. This Case Study discusses a patient with Lyme disease who refused antibiotic therapy during the first 4 years of her illness and demonstrates that antibiotic therapy is still likely to be effective, even following a long-term infection withBorrelia burgdorferi.
In this Case Study, the authors describe a patient with systemic lupus erythematosus and diffuse alveolar hemorrhage whose condition did not respond to high-dose corticosteroid therapy. Disease remission was achieved following treatment with umbilical-cord-derived mesenchymal stem cell transplantation.
