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    The use of artificial intelligence (AI), including machine learning and large language models, is revolutionizing health care, from drug discovery and development, through to applications in the risk stratification, diagnosis, imaging, monitoring, prognostication, and pharmacological and surgical treatment of patients.

    Image: V. Summersby / Springer Nature Limited

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    Research into women’s health has suffered from historical neglect and lack of funding.

    Image: Lara Crow/Springer Nature Limited

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    To celebrate the 15th anniversary of Nature Reviews Neurology, we present a series of Comment articles on the theme of "neurology at the crossroads", highlighting areas of neurology in which a turning point has been reached that necessitates a change in thinking. The anniversary issue also includes two Perspectives on the neurological consequences of COVID-19 and is accompanied by an online collection containing some of our most-cited articles from the past 15 years.

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    The 2020 Nobel Prize in Chemistry has been awarded to Emmanuelle Charpentier and Jennifer Doudna for their pioneering work in gene-editing.

    Image: Springer Nature/The Nobel Foundation/Imagesource

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    The Key Advances in Medicine 2019 collection, a collaborative effort from the eight clinical Nature Reviews journals, offers expert insight into the most important discoveries made in 2018, and is an essential resource for students, physicians and clinical researchers.

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    The Key Advances in Neurology collection offers expert insight into the most important discoveries made each year, and is an essential resource for students, physicians and clinical researchers.

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    Autoimmunity is an underlying cause of many diseases. This collection of Research, Reviews and News articles from several Nature journals covers the latest advances in genetic and epigenetic research into autoimmunity and autoimmune diseases.

    Image: Susanne Harris

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    To mark the reclassification of stroke as a neurological disease in the new International Classification of Disease, this collection brings you a selection of articles that address some of the latest and most exciting advances in stroke, including Reviews and commentaries written by world-leading stroke neurologists.

    Image: Philip Patenall

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    Much like our oceans, the world of clinical and biomedical research is vast, fast-paced, dynamic and full of unanswered questions. In 2017, numerous advances were made that could change the tide of efforts to fight disease. The Key Advances in Medicine eBook distils the major discoveries made in 2017 and highlights trends to look out for in 2018.

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    2017 marks the 200th anniversary since James Parkinson published his Essay on the Shaking Palsy. To mark this event, Nature Reviews bring together a collection of cutting edge articles that summarize the current basic and clinical research in Parkinson disease.

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    The past 10 years has seen great advances in the understanding and treatment of human disease. For expert perspectives on the most important breakthroughs, don't miss the FREE A Decade in Medicine eBook. In this special collection of 47 articles, leading experts highlight the most important advances in eight medical specialties between 2004 and 2015, and comment on future developments in their fields.