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A recent study finds that upregulation of nutrient-permeable channels in the parasitophorous vacuole membrane increases the acquisition of amino acids by artemisinin-resistant parasites to compensate for fitness costs.
This month’s Under the Lens discusses how recent advanced microscopy studies have provided insights into key target-search mechanisms that allow the recombinase RecA to rapidly and efficiently find homology for DNA repair.
This Genome Watch article highlights how technical advances have enabled the identification of short protein-coding open reading frames and thus the discovery of hidden small proteins.
A carefully controlled study finds that restricted dietary preferences might underlie the association between autism spectrum disorder and gut microbiome changes.
This study provides insights into the neuroinvasive mechanism of neurotropic alphaherpesviruses, which involves viral assimilation and repurposing of a cellular motor protein.
This Genome Watch highlights how the SARS-CoV-2 pandemic laid the groundwork for continued use of real-time genomic epidemiology for public health responses in low-and-middle-income countries.
A recent study provides evidence that the extracellular DNA-based architecture of bacterial biofilms relies on the rare left-handed helical form of DNA known as Z-DNA.
This study shows that segmented filamentous bacteria provide early protection against Citrobacter rodentium via a microbially derived metabolite that primes host innate immunity.
The successful treatment of polymicrobial infections is difficult, in part owing to inter-species interactions, which can alter antibiotic susceptibility of the bacteria. This study, focusing on cystic fibrosis, shows that multi-drug resistant Stenotrophomonas maltophilia can provide protection against imipenem to sensitive Pseudomonas aeruginosa.
An experimental evolution study showed that the cost of plasmid carriage can be caused by genetic conflicts between the plasmid and bacterial host chromosome.