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Two studies describe the design of safer genetically modified organisms that cannot grow in natural ecosystems because they require synthetic amino acids for growth.
This month's Genome Watch explores how genetic variation in restriction–modification systems fromStreptococcus pneumoniaecontributes to the defence against phages and to bacterial virulence.
Bassler and colleagues show that a small regulatory RNA fromVibrio harveyiregulates multiple target mRNAs by distinct mechanisms, which influences quorum sensing dynamics.
A new study shows that the cyclic provision of a single glycan by the Hawaiian bobtail squid to its bioluminescent symbiontVibrio fischericontributes to the persistence of their lifelong symbiosis.