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  • A new study identifies the mechanistic basis for host cell transformation byTheileriaspp. parasites.

    • Naomi Attar
    Research Highlight
  • Two studies describe the design of safer genetically modified organisms that cannot grow in natural ecosystems because they require synthetic amino acids for growth.

    • Cláudio Nunes-Alves
    Research Highlight
  • This study identifies CyRPA as the anchor of an essentialPlasmodium falciparuminvasion complex at the merozoite surface.

    • Andrea Du Toit
    Research Highlight
  • This month's Genome Watch explores how genetic variation in restriction–modification systems fromStreptococcus pneumoniaecontributes to the defence against phages and to bacterial virulence.

    • John Lees
    • Rebecca A. Gladstone
    Genome Watch
  • This study identifies bacteriophage exclusion (BREX) as a novel bacterial defence system that protects against lytic and lysogenic phage infection.

    • Cláudio Nunes-Alves
    Research Highlight
  • Bassler and colleagues show that a small regulatory RNA fromVibrio harveyiregulates multiple target mRNAs by distinct mechanisms, which influences quorum sensing dynamics.

    • Darren J. Burgess
    Research Highlight
  • A study reports the discovery of a new antibiotic with a novel mechanism of action and a low propensity to select for resistance.

    • Christina Tobin Kåhrström
    Research Highlight
  • A new study shows that the cyclic provision of a single glycan by the Hawaiian bobtail squid to its bioluminescent symbiontVibrio fischericontributes to the persistence of their lifelong symbiosis.

    • Christina Tobin Kåhrström
    Research Highlight