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  • An RNA virus that infects mosquitoes is the first example of an animal virus with a multicomponent composition.

    • Naomi Attar
    Research Highlight
  • Two new studies investigate cell division in the human pathogensChlamydia trachomatis and Borreliaspp.

    • Naomi Attar
    Research Highlight
  • This study reports that the DENV non-structural protein NS4B induces elongation of mitochondria, and that this is linked to the formation of convoluted membranes, enhanced viral replication and impaired immune responses.

    • Andrea Du Toit
    Research Highlight
  • This study shows that dynamic pores in the capsid of HIV allow the import of substrates for reverse transcription, thereby shielding the reaction from the host cytosol.

    • Ursula Hofer
    Research Highlight
  • This study reports the identification of an antimicrobial factor that is produced by the nasal commensalStaphylococcus lugdunensis and impairs colonization of the human nose by Staphylococcus aureus.

    • Andrea Du Toit
    Research Highlight
  • This month's Genome Watch explores recent advances in the identification of species-level and strain-level diversity in microbiome studies, and highlights how these have provided insights into the tropism and persistence ofNeisseriaspp. in the human oral cavity.

    • James Hadfield
    • Sophia David
    Genome Watch
  • This Focus issue on bacterial growth, highlights the versatility and adaptability with which bacterial cells respond to their environmental and community context.

    Editorial
  • This study shows that the effectors SseF and SseG bind to mammalian ACBD3 to localizeSalmonella-containing vacuoles to the Golgi network.

    • Andrea Du Toit
    Research Highlight
  • Single-molecule, real-time sequencing shows that a phase variation-induced epigenetic switch controls colony morphology inStreptococcus pneumoniae.

    • Naomi Attar
    Research Highlight
  • Interstrain competition enables non-toxigenicBacteroides fragilisto exclude enterotoxic bacteria from the same species, thereby protecting the gut from inflammation and disease.

    • Naomi Attar
    Research Highlight
    • Elitza I. Tocheva
    • Davi R. Ortega
    • Grant J. Jensen
    Correspondence
  • This study shows that deletion of a dehydratase attenuatesMycobacterium abscessuspathogenicity, owing to decreased cord formation and intracellular growth impairment.

    • Andrea Du Toit
    Research Highlight
  • How did a gorilla-infectingPlasmodiumspecies jump to a human host?

    • William R. Proto
    Genome Watch