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When antibiotics were first introduced into widespread clinical use in the 1950s, it was generally believed that bacterial diseases No. longer constituted a public health threat. With the emergence of new infectious diseases, the re-emergence of old diseases, and the rise of antibiotic resistance, this early optimism has long since eroded. In this series of articles, we explore important issues relevant to the development and use of anti-infectives, including discussions on new approaches to regain the upper hand over infectious diseases.
