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Recently, virulence mechanisms beyond canonical drug resistance were uncovered that enableAcinetobacter baumanniito thrive in the health-care environment and cause infections in critically ill patients. Harding, Hennon and Feldman explore the molecular features that promote environmental persistence and the most recently identified virulence factors that enable successful human infection.
This study identified a metabolic pathway in members of the gut microbiota, which uses aromatic amino acids to produce small molecules with systemic effects.
This study reports that commensal enteric fungi provide protection against infection in local intestinal and non-intestinal systemic tissues and enhance systemic immunity.
In this Review, Husnik and McCutcheon discuss how horizontally transferred genes from bacteria become functional in eukaryotes and classify horizontal gene transfer events into two broad types: those that maintain pre-existing functions and those that add new functionality to the recipient, including altered host nutrition, protection and adaptation to extreme environments.
Listeria monocytogenesis a food-borne pathogen responsible for human listeriosis. In this Review, Radoshevich and Cossart discuss the most recent advances inL. monocytogenesphysiology, biology and pathogenesis.
Bacterial predation byAcinetobacter baylyi increases the rate of horizontal gene transfer from Escherichia coli, which leads to the acquisition of antibiotic resistance genes from prey cells.
This study identifies the environmental factors that are associated with changes in bacterial secondary metabolism across natural environments on a metagenome-wide scale.
This issue marks the 40th anniversary of the publication of the landmark article by Carl Woese and George Fox in which they proposed the Archaea as a third domain of life.