News & Comment

Pathobiont-specific peripherally derived regulatory T cells have an important role in maintaining gut homeostasis.

NK cells recruit cDC1s to the tumour microenviroment by producing the chemokines CCL5 and XCL1.

Intratumoural vaccination with immune-enhancing agents eradicates tumour metastases.

Chimeric antigen receptors that provide an antigen-dependent signal 3 to T cells have improved antitumour efficacy.

Jedd Wolchok describes a 1996 study by Alan Houghton and colleagues that showed how immune tolerance to self antigens on cancer cells could be overcome.

ER adaptor protein identified as key sensor of the bacterial cyclic dinucleotide c-di-AMP.

An NK cell activating receptor can recognize a cellular growth factor to limit tumour cell growth.

Group 2 innate lymphoid cells present endogenous lipids via CD1a to skin-resident T cells

Shane Crotty discusses a 2013 study by Barton Haynes and colleagues that beautifully illustrates the extreme capacity of a B cell response to evolve in real time to a viral infection.