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  • Class-switched memory B cells form secondary germinal centres during recall responses to further diversify the antibody repertoire.

    • Kirsty Minton
    Research Highlight

  • Key characteristics of human IgM+ memory B cells have been identified, including a high degree of similarity to IgG+memory B cells.

    • Elisabeth Kugelberg
    Research Highlight

  • Individual naive B cells show heterogeneity in their response to antigen-mediated activation.

    • Yvonne Bordon
    Research Highlight

  • Skin immunity can be promoted by bacterial skin commensals that induce distinct CD8+T cell responses and by adipocytes that produce antimicrobial peptides.

    • Elisabeth Kugelberg
    Research Highlight

  • PTEN maintains regulatory T cell lineage stability and immune homeostasis.

    • Olive Leavy
    Research Highlight

  • RIG-I induces a type III interferon response during hepatitis B virus infection and also directly interferes with viral replication.

    • Yvonne Bordon
    Research Highlight