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Classic psychedelics are being revisited as novel drug candidates. Researchers are investigating the efficacy of psychedelics for disorders such as depression and addiction. Facets of obesity pathophysiology are neurobiologically similar to these conditions, and we propose that obesity could be the next frontier in psychedelic research.
Control loop designs are widely present in biology but can undergo errors, which can be fixed using generic strategies. Loop designs in response to organismal stress exhibit distinct features and are under ongoing investigations. Understanding control theory as an organizing principle in biology creates a broader perspective on endocrine and non-endocrine systems.