News & Comment

TheIgh 3′ regulatory region (Igh3′ RR) can function over long distances to activate the transcription of translocated Myc.

How does ZEB1 regulate self-renewal and migration?

Hyperactive AID can result in widespread genomic damage and lymphoma.

The importance of understanding basic biology.

Signals from EphB receptors that trigger cell proliferation and migration are mediated by two distinct downstream pathways.

TAp63 induces senescence and suppresses tumour growth in vivo.

Missense mutations of IDH1 confer oncogenic gain-of-function properties.

A crucial aspect of tumour biology, inflammation, is often overlooked in biomarker studies and needs to be urgently addressed.

Several papers find that YAP1 has many important roles in tumorigenesis and tumour progression.