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A 2D material based liquid-crystal shows an extremely large optical anisotropy factor in the deep ultraviolet region, showing magnetically tunable birefringence.
A dual-ligand passivation system comprising photocrosslinkable ligands and dispersing ligands enables quantum dots to be universally compatible with solution-based patterning techniques.
Nanopatterned materials provide control over mechanical vibrations. This allows for the complete damping of vibrations over more than 5 GHz and for the propagation of hypersonic guided modes at room temperature.
The combination of catalytic platinum particles, nanozymes and a CRISPR-based reaction allows for the quantification of non-coding RNAs at the picomolar range. This assay, CrisprZyme, has a colorimetric readout and works at room temperature without preamplification.
Quantitative polymerase chain reaction allows the real-time detection of nucleic acids in human samples, representing a gold standard for infection detection, but it cannot be easily converted into a point-of-care approach. Here a strategy is proposed to leverage plasmonic polymerase chain reaction to achieve multiplexed, fluorescence detection of SARS-CoV-2 RNA from human saliva and nasal specimen, showing promise as a point-of-care approach.
Ultrafine catalysts are desirable for the reduction of fuel cell costs but are intrinsically unstable. Here the authors report graphene-nanopocket-encaged PtCo catalysts with exceptional durability under the demanding ultralow-Pt-loading condition while delivering a satisfactory fuel cell performance.
NMR measurements show that the interface between the inorganic and organic components can be tailored to design a highly conducting hybrid solid electrolyte.
While neutrophils are the first line of defence against infections and inflammation, their unrestricted recruitment and constant activation might result in prolonged inflammation and sharpening of specific pathological conditions. Here the authors develop a strategy to specifically target activated, pro-inflammatory neutrophils and neutrophil–platelet complexes to deliver therapeutics in the context of a murine model of venous thrombosis.
A phenylboronic acid-modified hetero-octameric Mycobacterium smegmatis porin A nanopore can directly distinguish 11 types of nucleoside monophosphates with a 0.996 accuracy.
Intrinsically stretchable quantum-dot-based semiconducting nanocomposites enable the realization of shape-tunable and colour-sensitive phototransistor arrays.
A non-volatile silicon photonics switch based on phase-change materials actuated by graphene heaters shows a switching energy density that is within an order of magnitude of the fundamental thermodynamic limit.
Magnetic skyrmions are topological spin textures that hold potential for the development of post-von Neumann computing schemes. In coupled ferrimagnetic insulators, pinning effects and intentional distortions can lead to a ratchet-like current-driven motion of skyrmion bubbles.
Li-metal surfaces can be effectively protected against corrosion using fluoroethylene carbonate, leading to a conformal and stable solid–electrolyte interphase.
Cell heterogeneity might impact the delivery of lipid nanoparticles (LNPs) and efficacy of messenger RNA-based therapies in vivo. Here, the authors propose an approach to measure how various LNPs deliver DNA barcodes and mRNA to cells using single-cell RNA sequencing, providing a correlation between LNP uptake and the expression of specific genes that characterize cellular subtypes.
A theoretical model captures the thermodynamic principles behind the functioning of an out-of-equilibrium photoactivated artificial molecular pump in a quantitative manner.
Nicotinamide adenine dinucleotide (NAD+) is an immune modulator that was suggested as a potential treatment for sepsis, but its in vivo benefits are contradictory and its low bioavailability as a free drug hampers potential clinical translation. Here the authors show that using a lipid-coated nanoparticle to deliver NAD+ to the cell cytosol can effectively replenish the intracellular content of NAD+ and reduce the extent of the inflammatory response in mouse models of sepsis.
Light harvesting in photosynthesis and photovoltaics may rely on quantum-coherent energy transfer, but experimental verification is hindered by the lossy nature of the molecular systems. Subnanometre-resolved electroluminescence spectroscopy now reveals wavelike intermolecular electronic energy transfer through quantum coherence in artificially constructed donor–acceptor heterodimers at the single-molecule level.
Nanostructured fibres with highly aligned and alternating crystalline and amorphous domains created from triblock copolymers exhibit excellent mechanical properties, multi-trigger actuation, high-performance contraction and on/off rotation.