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By pushing throughput, single-cell transcript profiling can replace marker-based sorting and bulk RNA sequencing to redefine tissues from the bottom up.
Nature Methods is dedicated to publishing methodological developments for basic biological research. Yet many papers that we receive, and some that we publish, also have later-stage applications. Where do we draw the line of editorial scope?
A new device for injecting membrane-protein microcrystals into the path of an X-ray free-electron laser beam improves the efficiency of serial femtosecond crystallography.