Articles in 2008

Splenic marginal zone B cells take up blood-borne antigens. These B cells are now reported to continuously transport antigens to the follicles, a process that ensures efficient delivery of blood-borne antigens to follicular dendritic cells.

Picking up where pharmaceutical companies have left off, new academic science coalitions are using innovative techniques to hunt for new antibiotics.

Mentoring and networking are critical components for success in science. Here the importance and steps required for good mentoring and networking are described.

Over 20 years have passed since the discovery of NF-κB and its signaling pathways, yet additional participants continue to be identified. The highly conserved protein Akirin is such an example.

The cytokines IFN-γ and IL-12, along with the transcription factors STAT4 and T-bet, are necessary for driving T_H1 development. Fresh data now indicate that the transcription factor IRF1 is also essential in this process.

Phagocytosis of apoptotic cells by macrophages occurs through recognition of specific molecules on the surfaces of apoptotic cells by receptors on macrophages. Three recent studies add to the understanding of this process.