Reviews & Analysis

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  • The primary causes of dramatic variations in volcanic flux and composition along strike in subduction zones remain largely unknown. Here we use a promising new approach to show that along-strike volcanic variability in the Quaternary Cascades Arc is primarily due to variations in the flux of basalt into the base of the crust, rather than crustal magma storage.

    • C. B. Till
    • A. J. R. Kent
    • B. W. Pitcher
    PerspectiveOpen Access
  • Given the recent growing interest in interorganelle membrane contact sites, the field will benefit from clear rules to define and study them. In this Perspective, a panel of experts aims to provide this growing field with guidelines for experimental definition and analysis.

    • Luca Scorrano
    • Maria Antonietta De Matteis
    • Maya Schuldiner
    PerspectiveOpen Access
  • How can scientists and policymakers work together to reduce the health impacts of air pollution? In this review paper, the authors discuss the interplay between advances in environmental exposure assessment and policy advances to tackle pollution in a focused way.

    • Andrew Caplin
    • Masoud Ghandehari
    • George Thurston
    Review ArticleOpen Access
  • ADP-ribose erasing enzymes are increasingly recognized as critical regulators of protein ADP-ribosylation dynamics in living systems. Here, the authors review recent advances in the discovery and characterization of ADP-ribose erasers and discuss their role within the cellular ADP-ribosylation machinery.

    • Julia O’Sullivan
    • Maria Tedim Ferreira
    • Guy G. Poirier
    Review ArticleOpen Access
  • Halide lead perovskites have emerged recently as possible candidates for high performance radiation detectors besides efficient solar cells. Here Wei et al. review the recent progress on perovskite based radiation detectors and suggest that they may compete with the conventional counterparts.

    • Haotong Wei
    • Jinsong Huang
    Review ArticleOpen Access
  • Biological circadian rhythms maintain a period close to 24 h in coordination with the Earth’s fixed rotational period. Here Webb et al. discuss how external cues continuously adjust phase and period, viewing the oscillator as a dynamically-adjusted plastic system rather than tightly-coupled cogs in a mechanical clock.

    • Alex A. R. Webb
    • Motohide Seki
    • Camila Caldana
    PerspectiveOpen Access
  • The evolution of the Antarctic Ice Sheet is driven by a combination of climate forcing and non-climatic feedbacks. In this review, the authors focus on feedbacks between the Antarctic Ice Sheet and the solid Earth, and the role of these feedbacks in shaping the response of the ice sheet to past and future climate changes.

    • Pippa L. Whitehouse
    • Natalya Gomez
    • Douglas A. Wiens
    Review ArticleOpen Access