Reviews & Analysis

The structure of complex microbial communities is resolved by considering co-variation of gene abundance.

Manipulating the stem cell niche could provide new ways of coaxing stem cells to repair damaged tissues.

Organ-level physiology is recapitulated in vitro by culturing cells in perfused, microfluidic devices.

Clinical imaging is indispensable in cell therapy to monitor tissue repair and the fate of transplanted cells.

Strategies for inducing immunological tolerance to transplanted cells are an important component of regenerative therapies.

3D bioprinting of tissues and organs will find application in tissue engineering, research, drug discovery and toxicology.

Simultaneous measurement of paired TCR sequences and gene expression in single T cells improves the characterization of T cells.

New fabric-like sensors measure and transmit mechanical strain on the skin with unprecedented sensitivity.

Clarification of the genetic relationships among species opens new possibilities for enhancing citrus diversity and disease resistance.

Human pluripotent stem cells can be coaxed into a pure population of definitive hematopoietic cells.

Primary human cells provide mechanistic information for toxicology studies.

Using a cell as an RNA sequencing chip enables spatial analyses of the transcriptome at subcellular resolution.

The synthetic biology research community describes a standard language for exchanging designs of biological 'parts'.

The goal of characterizing solid-tumor genomes with nothing more than a blood sample is now within reach.

Incorporation of a new unnatural amino acid during protein synthesis enables proteomic profiling of specific cell types in whole animals.

Reducing the glycan heterogeneity of recombinant proteins may improve the efficacy of biopharmaceuticals.

Jeck and Sharpless review recent advances in sequencing, bioinformatics and biochemical analyses that have uncovered numerous circular RNA transcripts in mammalian cells.