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CO is a vital building block in organic synthesis but, due to its toxicity, storage and transport can be problematic. This review focuses on the methods — both chemical and electrochemical — for the in situ generation of CO from CO2, and its subsequent incorporation into chemicals through catalytic means.
Chemical and biological catalysts provide distinct advantages and disadvantages to the synthetic chemist. This Review focuses on efforts to combine chemo- and biocatalysts, outlining the opportunities achievable by this approach and also efforts to overcome any incompatibilities between these different systems.
