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Unique proteolipid vehicle (PLV) technology developed by Entos Pharmaceuticals is broadening the scope for biopharma to deliver nucleic-acid payoffs to target cells throughout the body, paving the way for a new generation of curative drugs.
Genialis is the RNA biomarker company; it espouses a people-first approach to machine learning–driven biomarker discovery. For targeted therapies to benefit the most patients possible, Genialis develops predictive biomarkers to guide treatment decisions. The company’s next-generation biomarkers work for real patients by informing targeted treatment decisions for better outcomes.
Philadelphia’s Aro Biotherapeutics has developed a novel RNA platform that leverages Centyrin proteins to deliver oligonucleotides to muscle and immune cells.
Primrose Bio’s advanced technology for manufacturing nucleic acids and proteins makes it the partner of choice for pharma companies developing new vaccines, therapeutics and bio-based products.
Through its innovative asymmetric siRNA platforms, OliX Pharmaceuticals is opening up huge opportunities in RNA interference-therapeutic development to address unmet needs for various indications spanning the liver, eye, skin, and beyond.
Azor Biotek is applying artificial intelligence solutions to the design and development of tailored, highly specific, novel small molecules, tapping into the vast potential of RNA drug targets.
Cancer Research Horizons (CRH) is harnessing the skills, expertise, and research network of its parent organization to speed-up the discovery and development of transformative oncology drugs, improve patient outcomes, and advance assets for biopharma partners.
Visionary investment in mRNA technology platforms is allowing ST PHARM and its two startups, Levatio Therapeutics and Vernagen, to foster partnerships and advance the development of cutting-edge RNA-based drugs and vaccines.
NurExone has created ExoTherapy, a cutting-edge exosome-based drug-delivery platform, and is currently developing its lead product, ExoPTEN, as a novel therapy for acute spinal cord injuries.
UK-based Broken String Biosciences is developing a commercial analytics platform for CRISPR therapeutics safety, a space in growing need of a gold standard solution for measuring off-target gene editing.
As Pandorum Technologies’ bioengineered ‘liquid cornea’, Kuragenx, is about to enter a first-in-human study for vision restoration in patients suffering from corneal blindness, the company is extending its proprietary technology platform to develop advanced exosome-based therapeutics for lung and liver regeneration.
With its unique and proprietary genetically modified adipocyte (GMAC) platform, CellGenTech is developing novel ex vivo gene therapies and has achieved the first-in-human study of an adipocyte-based gene therapy.
Pennsylvania-based Ocugen is a fully integrated, patient-centric biotech company focused on the development of vaccines in support of public health, and gene and cell therapies targeting unmet medical needs, all based on its three scientific platforms.
By engineering naturally existing arrestin domain-containing protein 1 (ARRDC1)-mediated microvesicles (known as ARMMs), Vesigen Therapeutics’ platform enables the effective delivery of novel biotherapeutics to specific tissues and cell types.
bit.bio is a synthetic biology company that uses its cell identity coding platform to reprogram induced pluripotent stem cells to create any human cell type.
Rapidly responding to the needs of the evolving oncology landscape, AstraZeneca is focused on sourcing transformational programs and technologies, whilst nurturing mutually beneficial partnerships to deliver innovative treatment strategies to patients.
One-carbon Therapeutics has developed a novel method to target the vulnerability of cancer cells that interrupts a pathway used by tumor cells to maintain a high rate of proliferation.