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  • Protocol Review
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Compliance Considerations

Lab Animal volume 51, page 3 (2022)Cite this article

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The Protocol Review coordinators offer the following compliance considerations:

Dr. Guaio’s procurement of tumor biopsy tissue would not require IACUC review and approval if Dr. Ty is performing a procedure for clinical reasons and excess tissue was given to Guaio1. However, the collection of tissues for research activities (regardless of the source of funding) requires IACUC review and approval prior to the initiation of the animal activities2. Consequently, the collection of tissues under the described circumstances would be considered non-compliance. Furthermore, the administration of an experimental substance, as detailed in the next paragraph, also requires IACUC review and approval, which Guaio did not secure.

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References

  1. NIH/OLAW, Frequently Asked Questions (FAQs) PHS Policy on Humane Care and Use of Laboratory Animals, Does the PHS Policy apply to use of animal tissue or materials obtained from dead animals? https://olaw.nih.gov/faqs#/guidance/faqs?anchor=question50287

  2. Animal Welfare Act, § 2132 https://www.aphis.usda.gov/animal_welfare/downloads/bluebook-ac-awa.pdf

  3. AVMA, AVMA Animal Health Studies Database - Learn About Veterinary Clinical Studies, https://ebusiness.avma.org/aahsd/more_info/veterinary_clinical_studies.aspx

  4. USDA/APHIS, VETERINARY SERVICES MEMORANDUM NO. 800.301 https://www.aphis.usda.gov/animal_health/vet_biologics/publications/memo_800_301.pdf

  5. Greer, W. & Danridge, L. Lab Anim. (NY) 47, 92 (2018).

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Authors and Affiliations

  1. Animal Care & Use Office, University of Michigan, Ann Arbor, Michigan, USA

    Lauren Danridge & Bill Greer

Authors
  1. Lauren Danridge
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  2. Bill Greer
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Correspondence to Lauren Danridge or Bill Greer.

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Danridge, L., Greer, B. Compliance Considerations. Lab Anim 51, 3 (2022). https://doi.org/10.1038/s41684-021-00893-x

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