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Genetic therapies

Lipid nanoparticles target haematopoietic stem cells

Nature Nanotechnology (2024)Cite this article

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Genetic therapies are delivered to haematopoietic stem cells using targeted lipid nanoparticles.

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Fig. 1: Haematopoietic stem cell-targeting lipid nanoparticles (LNPs) reach the bone marrow to deliver genetic medicines.

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Authors and Affiliations

  1. Global Investigative Toxicology, Preclinical Safety, Sanofi, Cambridge, MA, USA

    Dimitrios Bitounis

  2. Department of Pharmaceutical Sciences, School of Pharmacy and Pharmaceutical Sciences, Northeastern University, Boston, MA, USA

    Mansoor M. Amiji

  3. Department of Chemical Engineering, College of Engineering, Northeastern University, Boston, MA, USA

    Mansoor M. Amiji

Authors
  1. Dimitrios Bitounis
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  2. Mansoor M. Amiji
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Correspondence to Mansoor M. Amiji.

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Competing interests

D.B. is an employee of Sanofi US. M.M.A. declares no competing interests. The views expressed here are those of the authors and do not necessarily reflect the views of their employers.

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Bitounis, D., Amiji, M.M. Lipid nanoparticles target haematopoietic stem cells. Nat. Nanotechnol. (2024). https://doi.org/10.1038/s41565-024-01682-6

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