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DNA NANOTECHNOLOGY

A DNA nanodevice boosts tumour immunity

Nature Nanotechnology volume 16, pages 1306–1307 (2021)Cite this article

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A DNA nanodevice that selectively modulates the lysosomal protease activity in tumour-associated macrophages, increasing their antigen presentation ability, attenuates tumour growth in vivo.

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Fig. 1: Designer DNA nanodevice for the enhancement of anti-tumour immunity.

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Authors and Affiliations

  1. Interdisciplinary Research Center, Shanghai Synchrotron Radiation Facility, Zhangjiang Laboratory, Shanghai Advanced Research Institute, Chinese Academy of Sciences, Shanghai, China

    Jiang Li

  2. School of Chemistry and Chemical Engineering, Frontiers Science Center for Transformative Molecules and National Center for Translational Medicine, Shanghai Jiao Tong University, Shanghai, China

    Chunhai Fan

  3. Institute of Molecular Medicine, Shanghai Key Laboratory for Nucleic Acids Chemistry and Nanomedicine, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China

    Chunhai Fan

Authors
  1. Jiang Li
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  2. Chunhai Fan
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Correspondence to Jiang Li or Chunhai Fan.

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Li, J., Fan, C. A DNA nanodevice boosts tumour immunity. Nat. Nanotechnol. 16, 1306–1307 (2021). https://doi.org/10.1038/s41565-021-01002-2

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