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More need to optimize the prediction model of sFlt- 1/PIGF ratio and ambulatory blood pressure monitoring in preeclampsia

Hypertension Research volume 47, pages 1438–1439 (2024)Cite this article

Suggestions from Professor Salazar MR’s team are constructive. The detailed insights on ABPM(Ambulatory blood pressure monitoring) in PE(Pre-eclampsia) development from them are similar [1]. However, due to differences in the purpose, methods, and research population, nocturnal and masked hypertension as binary variables are not used in the analysis on preeclampsia(PE), but more suitable for subsequent research.

The association between nocturnal hypertension and the development of PE is consistent in recent studies [2], which is further confirmed in the research by the synergy relationship of sFlt-1/PIGF ratio [3]. But it needs to be noted that nocturnal hypertension is treated as a binary variable, while sFlt-1/PIGF ratio is treated as a continuous variable. In order to explore the relationship and synergy between sFlt-1/PIGF ratio levels and ABPM parameters, both continuous variables could be more suitable.

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References

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Authors and Affiliations

  1. Department of Obstetrics, Guangzhou Women and Children’s Medical Center, Guangzhou Medical University, Guangzhou, China

    Yunshan Chen, Xiuyu Pan & Huishu Liu

  2. School of Health Management, Southern Medical University, Guangzhou, Guangdong, 510515, China

    Guochun Xiang

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  1. Yunshan Chen
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Correspondence to Huishu Liu.

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Chen, Y., Pan, X., Xiang, G. et al. More need to optimize the prediction model of sFlt- 1/PIGF ratio and ambulatory blood pressure monitoring in preeclampsia. Hypertens Res 47, 1438–1439 (2024). https://doi.org/10.1038/s41440-024-01620-y

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