Functional MRI (fMRI) is increasingly used in efforts to unravel the neuropathological processes of neuropsychiatric systemic lupus erythematosus (NPSLE). Standardization of scan protocols, imaging expertise and disease-related confounders of neuronal activities remain major challenges to the use of fMRI in the diagnosis and prognosis of NPSLE.
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Acknowledgements
The authors' work is supported by the CS-IRG grant, National Medical Research Council, Singapore (R-172-000-337-511).
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Supplementary Table 1
Summary of 10 fMRI studies in patients with SLE. (DOCX 34 kb)
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Mak, A., Tay, S. Functional MRI in SLE—the current state. Nat Rev Rheumatol 11, 686–687 (2015). https://doi.org/10.1038/nrrheum.2015.143
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DOI: https://doi.org/10.1038/nrrheum.2015.143