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Therapy

What should we do after the failure of a first anti-TNF?

Golimumab effectively reduces the signs and symptoms of active rheumatoid arthritis in patients who have previously failed treatment with at least one tumor necrosis factor inhibitor. Is it now time to develop strategies for sequential drug administration?

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Correspondence to Chris Deighton.

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Competing interests

C. Deighton has been involved in speakers bureaus (honoraria) for and received grant/research support from Wyeth and Abbott, and has received grant/research support from Schering-Plough and Roche.

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Deighton, C. What should we do after the failure of a first anti-TNF?. Nat Rev Rheumatol 5, 596–597 (2009). https://doi.org/10.1038/nrrheum.2009.212

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