More than a decade after the first paper detailing the immense diversity of human microflora (Proc. Natl. Acad. Sci. USA 96, 14547–14552, 1999), the microbiome research literature has expanded enormously. This reflects an influx of funding from such agencies as the US National Institutes of Health and the European Union's MetaHIT project. In contrast to publications, microbiome-related patents have increased less markedly. Recently published trials underscore the clinical promise of this research.

Publications over time

Patenting related to the microbiome

Notable recent trial and clinical study results

Top ten institutions receiving microbiome funding

Funding for microbiome research

Top ten cited research articles in human microbiome research (2003–2013)