We thank Rai and Mughal1 for their comments on our article.2 The comments raise an important point about not only peripheral blood pressure (BP) but also central BP for the management of hypertension. As he mentioned, many papers have recently reported on the association between central BP and target organ damage.3, 4, 5, 6 However, in all of those studies, central BP was evaluated in a clinical setting. In our present guideline, we focused on home BP monitoring, because out-of-office BP has long been recognized to have advantages over traditional clinic BP measurements for the management of hypertension.7, 8 Unfortunately, as there have been no reports on the efficacy of home measurement of central BP for the management of hypertension, we could not include central BP recommendations in the present guideline. Recently, a device incorporating the indices for not only conventional BP but also central BP throughout a 24-h period has been developed.9, 10 Therefore, this device would be available for studying the association between out-of-office central BP, and target organ damage and cardiovascular events. From this time onwards, out-of-office central BP data should be accumulated for analysis in future studies.
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Hoshide, S., Imai, Y. & Kario, K. Response to Rai. Hypertens Res 36, 88 (2013). https://doi.org/10.1038/hr.2012.168
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DOI: https://doi.org/10.1038/hr.2012.168