Collection 

Regulatory T cells

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Regulatory T cells are a critical part of the immune system, preventing autoimmune diseases and limiting chronic inflammatory diseases like asthma and inflammatory bowel disease. However, these immunosuppressive cells can also prevent the establishment of protective immune responses and limit anti-tumour immunity. Regulatory T cells can induce suppression in several ways, including via inhibitory cytokines, cytolysis, metabolic disruption, and modulation of dendritic-cell maturation or function. However, the relationship between these mechanisms, as well as their relative importance, remains unclear. 

This Collection welcomes original research on all aspects of regulatory T cells, including their development, their function, and their roles in conditions and diseases such as autoimmunity and cancer.

 

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Lymphocyte, closeup view of T-cell or B-cell

Editors

  • Khalid Muhammad, PhD

    Associate Professor, Department of Biology, College of Science, UAE University, Al Ain, UAE.

  • Shresh Pathak, PhD

    Assistant Professor, Institute of Molecular Medicine, Feinstein Institutes for Medical Research, Manhasset, New York, USA Assistant Professor, Department of Otolaryngology, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Hempstead, New York, USA

Khalid Muhammad, PhD, Associate Professor, Department of Biology, College of Science, UAE University, Al Ain, UAE.

Khalid Muhammad is Associate Professor of Molecular Immunology at UAE University, UAE.  He has several years of research experience in the field of autoimmunity and inflammatory diseases by exploring role of T and B cells at transcriptional level. Dr. Muhammad has been an Editorial Board Member for Scientific Reports since 2024.

 

Shresh Pathak, PhD, Assistant Professor, Institute of Molecular Medicine, Feinstein Institutes for Medical Research, Manhasset, New York, USA & Assistant Professor, Department of Otolaryngology, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Hempstead, New York, USA

Shresh Pathak is Assistant Professor in Institute of Molecular Medicine, Feinstein Institutes for Medical Research and in the Department of Otolaryngology, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell. Dr. Pathak also has a secondary appointment at Albert Einstein College of Medicine as Adjunct Clinical Assistant Professor, Department of Otorhinolaryngology Head & Neck Surgery. Dr. Pathak has over two decades of research experience in signaling pathways involved in various diseases. He is involved in understanding various molecular mechanisms related to autoimmune inner ear disease (AIED) and developing potential alternate therapies for AIED patients who are corticosteroid resistant. Dr. Pathak has been an Editorial Board Member for Scientific Reports since 2022.