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| Open AccessHighly functionalized β-lactams and 2-ketopiperazines as TRPM8 antagonists with antiallodynic activity
- M.Ángeles Bonache
- , Cristina Martín-Escura
- & Rosario González-Muñiz
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Article
| Open AccessCurcumin enhances cisplatin-induced human laryngeal squamous cancer cell death through activation of TRPM2 channel and mitochondrial oxidative stress
- Sinem Gökçe Kütük
- , Gökçen Gökçe
- & Mustafa Nazıroğlu
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Article
| Open AccessCompetitive Interactions between PIRT, the Cold Sensing Ion Channel TRPM8, and PIP2 Suggest a Mechanism for Regulation
- Nicholas J. Sisco
- , Cole V. M. Helsell
- & Wade D. Van Horn
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Article
| Open AccessMiltefosine treatment reduces visceral hypersensitivity in a rat model for irritable bowel syndrome via multiple mechanisms
- Sara Botschuijver
- , Sophie A. van Diest
- & René M. van den Wijngaard
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Article
| Open AccessIon Permeation Mechanism in Epithelial Calcium Channel TRVP6
- Serzhan Sakipov
- , Alexander I. Sobolevsky
- & Maria G. Kurnikova
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Article
| Open AccessTRPV4-mediates oscillatory fluid shear mechanotransduction in mesenchymal stem cells in part via the primary cilium
- Michele A. Corrigan
- , Gillian P. Johnson
- & David A. Hoey
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Article
| Open AccessInactivation of TRPM7 kinase in mice results in enlarged spleens, reduced T-cell proliferation and diminished store-operated calcium entry
- Pavani Beesetty
- , Krystyna B. Wieczerzak
- & J. Ashot Kozak
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Article
| Open AccessNa+ entry through heteromeric TRPC4/C1 channels mediates (−)Englerin A-induced cytotoxicity in synovial sarcoma cells
- Katsuhiko Muraki
- , Kaori Ohnishi
- & David J. Beech
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| Open AccessSynthesis, high-throughput screening and pharmacological characterization of β–lactam derivatives as TRPM8 antagonists
- Roberto de la Torre-Martínez
- , M. Angeles Bonache
- & Rosario González-Muñiz
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Article
| Open AccessExpression and Purification of the Pain Receptor TRPV1 for Spectroscopic Analysis
- Phanindra Velisetty
- , Richard A. Stein
- & Julio F. Cordero-Morales
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Article
| Open AccessA-Kinase Anchoring Protein 79/150 Scaffolds Transient Receptor Potential A 1 Phosphorylation and Sensitization by Metabotropic Glutamate Receptor Activation
- Allison Doyle Brackley
- , Ruben Gomez
- & Nathaniel A. Jeske
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Article
| Open AccessPolysulfides (H2Sn) produced from the interaction of hydrogen sulfide (H2S) and nitric oxide (NO) activate TRPA1 channels
- Ryo Miyamoto
- , Shin Koike
- & Hideo Kimura
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Article
| Open AccessA Gate Hinge Controls the Epithelial Calcium Channel TRPV5
- Jenny van der Wijst
- , Elizabeth H. Leunissen
- & Joost G. Hoenderop
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Article
| Open AccessMass Spectrometric Analysis of TRPM6 and TRPM7 Phosphorylation Reveals Regulatory Mechanisms of the Channel-Kinases
- Na Cai
- , Zhiyong Bai
- & Loren W. Runnels
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Article
| Open AccessMitsugumin 53 regulates extracellular Ca2+ entry and intracellular Ca2+ release via Orai1 and RyR1 in skeletal muscle
- Mi Kyoung Ahn
- , Keon Jin Lee
- & Eun Hui Lee
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| Open AccessSynthetic small molecule GLP-1 secretagogues prepared by means of a three-component indole annulation strategy
- Oleg G. Chepurny
- , Colin A. Leech
- & George G. Holz
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| Open AccessA molecular determinant of phosphoinositide affinity in mammalian TRPV channels
- Phanindra Velisetty
- , Istvan Borbiro
- & Tibor Rohacs
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Article
| Open AccessSelective potentiation of 2-APB-induced activation of TRPV1–3 channels by acid
- Luna Gao
- , Pu Yang
- & Jing Yao
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Article
| Open AccessAcid-induced off-response of PKD2L1 channel in Xenopus oocytes and its regulation by Ca2+
- Shaimaa Hussein
- , Wang Zheng
- & Xing-Zhen Chen
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Article
| Open AccessThe pain receptor TRPV1 displays agonist-dependent activation stoichiometry
- Adina Hazan
- , Rakesh Kumar
- & Avi Priel