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| Open AccessBehavioral analysis of kainate receptor KO mice and the role of GluK3 subunit in anxiety
- Izumi Iida
- , Kohtarou Konno
- & Miho Terunuma
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| Open AccessKv3.4 regulates cell migration and invasion through TGF-β-induced epithelial–mesenchymal transition in A549 cells
- Hun Ju Sim
- , Mi Ri Kim
- & So Yeong Lee
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Article
| Open AccessThe combination of propylene glycol and vegetable glycerin e-cigarette aerosols induces airway inflammation and mucus hyperconcentration
- Michael D. Kim
- , Samuel Chung
- & Matthias Salathe
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| Open AccessHigh-throughput ligand profile characterization in novel cell lines expressing seven heterologous insect olfactory receptors for the detection of volatile plant biomarkers
- Katalin Zboray
- , Adam V. Toth
- & Peter Lukacs
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| Open AccessDetermining the structure of the bacterial voltage-gated sodium channel NaChBac embedded in liposomes by cryo electron tomography and subtomogram averaging
- Shih-Ying Scott Chang
- , Patricia M. Dijkman
- & Misha Kudryashev
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| Open AccessFunctional characterization of the transient receptor potential melastatin 2 (TRPM2) cation channel from Nematostella vectensis reconstituted into lipid bilayer
- Andras Szollosi
- & János Almássy
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| Open AccessFluorescence lifetime FRET assay for live-cell high-throughput screening of the cardiac SERCA pump yields multiple classes of small-molecule allosteric modulators
- Osha Roopnarine
- , Samantha L. Yuen
- & David D. Thomas
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| Open AccessA blue-shifted anion channelrhodopsin from the Colpodellida alga Vitrella brassicaformis
- Keiichi Kojima
- , Shiho Kawanishi
- & Yuki Sudo
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| Open AccessChannel activity of SARS-CoV-2 viroporin ORF3a inhibited by adamantanes and phenolic plant metabolites
- Marina Sherif Fam
- , Christine Adel Sedky
- & Ulrike Breitinger
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| Open AccessFerritin thresholds for cardiac and liver hemosiderosis in β-thalassemia patients: a diagnostic accuracy study
- Hadi Darvishi-Khezri
- , Aily Aliasgharian
- & Hossein Karami
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| Open AccessJaw1/LRMP increases Ca2+ influx upon GPCR stimulation with heterogeneous effect on the activity of each ITPR subtype
- Wataru Okumura
- , Takuma Kozono
- & Atsushi Nishikawa
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| Open AccessATP13A3 facilitates polyamine transport in human pancreatic cancer cells
- Vandana Sekhar
- , Thomas Andl
- & Otto Phanstiel IV
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| Open AccessFormation and function of OmpG or OmpA-incorporated liposomes using an in vitro translation system
- Koki Kamiya
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| Open AccessAI-based atomic force microscopy image analysis allows to predict electrochemical impedance spectra of defects in tethered bilayer membranes
- Tomas Raila
- , Tadas Penkauskas
- & Gintaras Valinčius
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| Open AccessBrCNGC gene family in field mustard: genome-wide identification, characterization, comparative synteny, evolution and expression profiling
- Akram Ali Baloch
- , Agha Muhammad Raza
- & Kaleem U. Kakar
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Article
| Open AccessCyFi-MAP: an interactive pathway-based resource for cystic fibrosis
- Catarina Pereira
- , Alexander Mazein
- & Andre O. Falcao
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| Open AccessMechanisms and consequences of casein kinase II and ankyrin-3 regulation of the epithelial Na+ channel
- Tarek Mohamed Abd El-Aziz
- , Antonio G. Soares
- & Jonathan M. Berman
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Article
| Open AccessStrictly regulated agonist-dependent activation of AMPA-R is the key characteristic of TAK-653 for robust synaptic responses and cognitive improvement
- Atsushi Suzuki
- , Akiyoshi Kunugi
- & Haruhide Kimura
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| Open AccessOuter membrane and phospholipid composition of the target membrane affect the antimicrobial potential of first- and second-generation lipophosphonoxins
- Klára Látrová
- , Noemi Havlová
- & Gabriela Mikušová
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| Open AccessThe effects of beta-cell mass and function, intercellular coupling, and islet synchrony on \({\text {Ca}}^{2+}\) dynamics
- Maryam Saadati
- & Yousef Jamali
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| Open AccessC subunit of the ATP synthase is an amyloidogenic calcium dependent channel-forming peptide with possible implications in mitochondrial permeability transition
- Giuseppe Federico Amodeo
- , Brenda Yasie Lee
- & Evgeny V. Pavlov
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| Open AccessFunctional NMDA receptors are expressed by human pulmonary artery smooth muscle cells
- Yi Na Dong
- , Fu-Chun Hsu
- & David R. Lynch
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| Open AccessIdentification and functional analysis of a biflavone as a novel inhibitor of transient receptor potential vanilloid 4-dependent atherogenic processes
- Mazen O. Alharbi
- , Bidisha Dutta
- & Shaik O. Rahaman
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| Open AccessPreference of Proteomonas sulcata anion channelrhodopsin for NO3− revealed using a pH electrode method
- Chihiro Kikuchi
- , Hina Kurane
- & Takashi Tsukamoto
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| Open AccessAltered functional properties of the codling moth Orco mutagenized in the intracellular loop-3
- Yuriy V. Bobkov
- , William B. Walker III
- & Alberto Maria Cattaneo
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Article
| Open AccessThe carboxy terminal coiled-coil modulates Orai1 internalization during meiosis
- Rawad Hodeify
- , Maya Dib
- & Khaled Machaca
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| Open AccessUnravelling the intricate cooperativity of subunit gating in P2X2 ion channels
- Christian Sattler
- , Thomas Eick
- & Klaus Benndorf
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| Open AccessToxic oligomers of the amyloidogenic HypF-N protein form pores in mitochondrial membranes
- Maria Ylenia Farrugia
- , Mario Caruana
- & Neville Vassallo
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| Open AccessA structure-based computational workflow to predict liability and binding modes of small molecules to hERG
- Subha Kalyaanamoorthy
- , Shawn M. Lamothe
- & Khaled H. Barakat
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Article
| Open AccessMitochondrial Calcium Uniporter (MCU) deficiency reveals an alternate path for Ca2+ uptake in photoreceptor mitochondria
- Celia M. Bisbach
- , Rachel A. Hutto
- & Susan E. Brockerhoff
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| Open AccessHighly functionalized β-lactams and 2-ketopiperazines as TRPM8 antagonists with antiallodynic activity
- M.Ángeles Bonache
- , Cristina Martín-Escura
- & Rosario González-Muñiz
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| Open AccessInsights on small molecule binding to the Hv1 proton channel from free energy calculations with molecular dynamics simulations
- Victoria T. Lim
- , Andrew D. Geragotelis
- & Douglas J. Tobias
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Article
| Open AccessUncovering a possible role of reactive oxygen species in magnetogenetics
- Matthew I. Brier
- , Jordan W. Mundell
- & Jonathan S. Dordick
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| Open AccessUnique cysteine-enriched, D2L5 and D4L6 extracellular loops in CaV3 T-type channels alter the passage and block of monovalent and divalent ions
- Wendy Guan
- , Robert F. Stephens
- & J. David Spafford
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| Open AccessMolecular and cellular correlates in Kv channel clustering: entropy-based regulation of cluster ion channel density
- Limor Lewin
- , Esraa Nsasra
- & Ofer Yifrach
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| Open AccessTransient Receptor Potential Vanilloid channel regulates fibroblast differentiation and airway remodeling by modulating redox signals through NADPH Oxidase 4
- Nosayba Al-Azzam
- , Lakshminarayan Reddy Teegala
- & Sailaja Paruchuri
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| Open AccessDrosophila taste neurons as an agonist-screening platform for P2X receptors
- Leanne Grimes
- , Julia Griffiths
- & Wynand van der Goes van Naters
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| Open AccessStructure-based engineering of anti-GFP nanobody tandems as ultra-high-affinity reagents for purification
- Ziyue Zhang
- , Yao Wang
- & Motoyuki Hattori
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| Open AccessBeyond hemostasis: a snake venom serine protease with potassium channel blocking and potential antitumor activities
- Johara Boldrini-França
- , Ernesto Lopes Pinheiro-Junior
- & Jan Tytgat
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| Open AccessSelective Binding of HSC70 and its Co-Chaperones to Structural Hotspots on CFTR
- Imad Baaklini
- , Conrado de Campos Gonçalves
- & Jason C. Young
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| Open AccessComplex approach for analysis of snake venom α-neurotoxins binding to HAP, the high-affinity peptide
- Denis S. Kudryavtsev
- , Valentin М. Tabakmakher
- & Victor I. Tsetlin
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| Open AccessNanodisc technology facilitates identification of monoclonal antibodies targeting multi-pass membrane proteins
- Bernd Gardill
- , Jerry Huang
- & Christy A. Thomson
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Article
| Open AccessCation permeability in CorA family of proteins
- Artem Stetsenko
- & Albert Guskov
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| Open AccessStructure-activity relationship studies of four novel 4-aminopyridine K+ channel blockers
- Sofia Rodríguez-Rangel
- , Alyssa D. Bravin
- & Jorge E. Sánchez-Rodríguez
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| Open AccessCa(2+)N It Be Measured? Detection of Extramitochondrial Calcium Movement With High-Resolution FluoRespirometry
- Anna Nászai
- , Emil Terhes
- & László Juhász
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| Open AccessA muscular hypotonia-associated STIM1 mutant at R429 induces abnormalities in intracellular Ca2+ movement and extracellular Ca2+ entry in skeletal muscle
- Jun Hee Choi
- , Mei Huang
- & Eun Hui Lee
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| Open AccessInvestigation and Restoration of BEST1 Activity in Patient-derived RPEs with Dominant Mutations
- Changyi Ji
- , Yao Li
- & Tingting Yang
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| Open AccessCurcumin enhances cisplatin-induced human laryngeal squamous cancer cell death through activation of TRPM2 channel and mitochondrial oxidative stress
- Sinem Gökçe Kütük
- , Gökçen Gökçe
- & Mustafa Nazıroğlu
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| Open AccessNanomolar-potency ‘co-potentiator’ therapy for cystic fibrosis caused by a defined subset of minimal function CFTR mutants
- Puay-Wah Phuan
- , Joseph-Anthony Tan
- & Alan S. Verkman