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ILC1 drive intestinal epithelial and matrix remodelling
Type-1 innate lymphoid cells have been shown to drive intestinal epithelial proliferation and extracellular matrix remodelling through TGF-β1 secretion, which could exacerbate inflammatory bowel disease comorbidities such as cancer and fibrosis.
- Geraldine M. Jowett
- , Michael D. A. Norman
- & Eileen Gentleman