Featured
-
-
Article
| Open AccessTenovin 3 induces apoptosis and ferroptosis in EGFR 19del non small cell lung cancer cells
- Sha Lv
- , Qianrong Pan
- & Xueping Lei
-
Article
| Open AccessComparison of efficacy and safety of equivalent doses of remimazolam versus propofol for gastroscopy anesthesia in elderly patients
- Di Chen
- , Min Liao
- & Hu Sun
-
Article
| Open AccessDesign, synthesis and bioactivity study on oxygen-heterocyclic-based pyran analogues as effective P-glycoprotein-mediated multidrug resistance in MCF-7/ADR cell
- Ashraf H. F. Abd El-Wahab
- , Rita M. A. Borik
- & Ahmed M. El-Agrody
-
Article
| Open AccessPodocalyxin promotes the formation of compact and chemoresistant cancer spheroids in high grade serous carcinoma
- Ngoc Le Tran
- , Yao Wang
- & Guiying Nie
-
Article
| Open AccessNetwork pharmacology, computational biology integrated surface plasmon resonance technology reveals the mechanism of ellagic acid against rotavirus
- Jiangang Zheng
- , Abdul Haseeb
- & Hejie Wang
-
Article
| Open AccessA new DNA aptamer which binds to SARS-CoV-2 spike protein and reduces pro-inflammatory response
- Woong Kim
- , Eun Su Song
- & Seok-Jun Kim
-
Article
| Open AccessCoumarin linked to 2-phenylbenzimidazole derivatives as potent α-glucosidase inhibitors
- Mina Sadeghi Ganjeh
- , Ali Mazlomifar
- & Shiva Khalili Moghaddam
-
Article
| Open AccessReal-time analysis of osteoclast resorption and fusion dynamics in response to bone resorption inhibitors
- Preety Panwar
- , Jacob Bastholm Olesen
- & Dieter Brömme
-
Article
| Open AccessEffect of sulfasalazine on ferroptosis during intestinal injury in rats after liver transplantation
- Wei Wu
- , Wenhao Bu
- & Yongwang Wang
-
Article
| Open AccessEscherichia coli has an undiscovered ability to inhibit the growth of both Gram-negative and Gram-positive bacteria
- Ertan Kastrat
- & Hai-Ping Cheng
-
Article
| Open AccessGEFormerDTA: drug target affinity prediction based on transformer graph for early fusion
- Youzhi Liu
- , Linlin Xing
- & Maozu Guo
-
Article
| Open AccessOvercoming radioresistance of breast cancer cells with MAP4K4 inhibitors
- Yun-Suk Kwon
- , Min-Gu Lee
- & Soyoung Kim
-
Article
| Open AccessPotential diagnostic and drug target markers in glioblastoma
- Hina Ahsan
- , Muhammad Asghar
- & Shaukat Iqbal Malik
-
Article
| Open AccessNetwork pharmacology analysis and experimental validation to explore the mechanism of kaempferol in the treatment of osteoporosis
- Qi Dong
- , Guoxia Ren
- & Dingjun Hao
-
Article
| Open AccessBackground and clinical significance of biomarker-based patient enrichment in non-small-cell lung cancer drug development
- Kenji Harada
- & Shunsuke Ono
-
Article
| Open AccessNuciferine reduces vascular leakage and improves cardiac function in acute myocardial infarction by regulating the PI3K/AKT pathway
- Wei Xie
- , Shumin Chen
- & Dongjin Wang
-
Article
| Open AccessFully connected-convolutional (FC-CNN) neural network based on hyperspectral images for rapid identification of P. ginseng growth years
- Xingfeng Chen
- , Hejuan Du
- & Shu Liu
-
Article
| Open AccessA comprehensive computational study to explore promising natural bioactive compounds targeting glycosyltransferase MurG in Escherichia coli for potential drug development
- Amneh Shtaiwi
- , Shafi Ullah Khan
- & Samir Chtita
-
Article
| Open AccessCorrelation analysis of disulfidptosis-related gene signatures with clinical prognosis and immunotherapy response in sarcoma
- Juan Xu
- , Kangwen Guo
- & Chao Wang
-
Article
| Open AccessValency based novel quantitative structure property relationship (QSPR) approach for predicting physical properties of polycyclic chemical compounds
- Ali Raza
- , Mishal Ismaeel
- & Fikadu Tesgera Tolasa
-
Article
| Open AccessPharmacokinetic and pharmacodynamic evaluation study of etomidate: a randomized, open-label, 2-period crossover study in healthy Chinese subjects
- Ying Ding
- , Nan-nan Chu
- & Qing He
-
Article
| Open Access1,2,3-triazole and chiral Schiff base hybrids as potential anticancer agents: DFT, molecular docking and ADME studies
- Yonas Belay
- , Alfred Muller
- & Abel K. Oyebamiji
-
Article
| Open AccessA highly selective mPGES-1 inhibitor to block abdominal aortic aneurysm progression in the angiotensin mouse model
- Lauren M. Weaver
- , Madeline J. Stewart
- & Chang-Guo Zhan
-
Article
| Open AccessN-benzyl-N-methyldecan-1-amine, derived from garlic, and its derivative alleviate 2,4-dinitrochlorobenzene-induced atopic dermatitis-like skin lesions in mice
- Ji Eun Kim
- , Phatcharaporn Budluang
- & Young-Hwa Chung
-
Article
| Open AccessLysine demethylase LSD1 is associated with stemness in EBV-positive B cell lymphoma
- Joo Hyun Kim
- , Chaehwa Park
- & Won Seog Kim
-
Article
| Open AccessEnhancing explainable SARS-CoV-2 vaccine development leveraging bee colony optimised Bi-LSTM, Bi-GRU models and bioinformatic analysis
- Dilber Uzun Ozsahin
- , Zubaida Said Ameen
- & Auwalu Saleh Mubarak
-
Article
| Open AccessDevelopment of a novel AAK1 inhibitor via Kinobeads-based screening
- Akari Yoshida
- , Satomi Ohtsuka
- & Hiroshi Tokumitsu
-
Article
| Open AccessExtracellular vesicles secreted from mesenchymal stem cells ameliorate renal ischemia reperfusion injury by delivering miR-100-5p targeting FKBP5/AKT axis
- Guo Chen
- , Xinyuan Li
- & Yuanbin Jiang
-
Article
| Open AccessCeratophyllum demersum the submerged macrophyte from the mining subsidence reservoir Nadrybie Poland as a source of anticancer agents
- Maciej Masłyk
- , Tomasz Lenard
- & Konrad Kubiński
-
Article
| Open AccessIn silico approaches for the identification of potential allergens among hypothetical proteins from Alternaria alternata and its functional annotation
- Rajamanikandan Sundararaj
- , Amala Mathimaran
- & Tsehaye Asmelash
-
Article
| Open Access5-HT_FAsTR: a versatile, label-free, high-throughput, fluorescence-based microplate assay to quantify serotonin transport and release
- Lina Bukowski
- , Markus Emanuel Strøm
- & Steffen Sinning
-
Article
| Open AccessRelationship between prediction accuracy and uncertainty in compound potency prediction using deep neural networks and control models
- Jannik P. Roth
- & Jürgen Bajorath
-
Article
| Open AccessAntiemetic activity of abietic acid possibly through the 5HT3 and muscarinic receptors interaction pathways
- Rubel Hasan
- , Abdulrahman Alshammari
- & Muhammad Torequl Islam
-
Article
| Open AccessPoint biserial correlation symbiotic organism search nanoengineering based drug delivery for tumor diagnosis
- Garima Shukla
- , Sofia Singh
- & Ben Othman Soufiene
-
Article
| Open AccessUnveiling potential drug targets for hyperparathyroidism through genetic insights via Mendelian randomization and colocalization analyses
- Bohong Chen
- , Lihui Wang
- & Na Hao
-
Article
| Open AccessMulti-omics pan-cancer analyses identify MCM4 as a promising prognostic and diagnostic biomarker
- Yanxing Li
- , Wentao Gao
- & Jianjun Li
-
Article
| Open AccessAnti-proliferative and apoptotic effect of cannabinoids on human pancreatic ductal adenocarcinoma xenograft in BALB/c nude mice model
- Trung Quang Le
- , Nuntana Meesiripan
- & Kasem Rattanapinyopituk
-
Article
| Open AccessThe roles of autophagy, ferroptosis and pyroptosis in the anti-ovarian cancer mechanism of harmine and their crosstalk
- Jun Zhu
- , Hong Zhu
- & Jun Gao
-
Article
| Open AccessAesculus hippocastanum extract and the main bioactive constituent β-escin as antivirals agents against coronaviruses, including SARS-CoV-2
- Freddy Armando Peñaranda Figueredo
- , Josefina Vicente
- & Carlos Alberto Bueno
-
Article
| Open AccessThe novel drug candidate S2/IAPinh improves survival in models of pancreatic and ovarian cancer
- Takaomi Hagi
- , Suwanna Vangveravong
- & Dirk Spitzer
-
Article
| Open AccessApplication of 32 factorial design for loratadine-loaded nanosponge in topical gel formulation: comprehensive in-vitro and ex vivo evaluations
- Durgaramani Sivadasan
- , Krishnaraju Venkatesan
- & Sami El Deeb
-
Article
| Open AccessPhytochemical composition and in vitro antioxidant and antimicrobial activities of Bersama abyssinica F. seed extracts
- Belayhun Alemu
- , Meseret Derbew Molla
- & Tadesse Asmamaw
-
Article
| Open AccessComputational identification of natural senotherapeutic compounds that mimic dasatinib based on gene expression data
- Franziska Meiners
- , Burkhard Hinz
- & Israel Barrantes
-
Article
| Open AccessDevelopment of extended pharmacokinetic models for propofol based on measured blood and brain concentrations
- Masayoshi Kawata
- , Atsushi Yonezawa
- & Yoshiki Arakawa
-
Article
| Open AccessUltra-high throughput-based screening for the discovery of antiplatelet drugs affecting receptor dependent calcium signaling dynamics
- Delia I. Fernández
- , Sara Troitiño
- & Johan W. M. Heemskerk
-
Article
| Open AccessTargeting the NTSR2/TrkB oncogenic pathway in chronic lymphocytic leukemia
- Léa Ikhlef
- , May Yassine
- & Paul-François Gallet
-
Article
| Open AccessCharacterization of human iPSC-derived sensory neurons and their functional assessment using multi electrode array
- Minami Hiranuma
- , Yuichi Okuda
- & Tomohisa Watanabe
-
Article
| Open AccessDigital pathology with artificial intelligence analysis provides insight to the efficacy of anti-fibrotic compounds in human 3D MASH model
- Radina Kostadinova
- , Simon Ströbel
- & Mathieu Petitjean
-
Article
| Open AccessEfficacy of silver nanoparticles against Trichinella spiralis in mice and the role of multivitamin in alleviating its toxicity
- Noha Madbouly Taha
- , Fady Sayed Youssef
- & Reem M. Ramadan