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  • This study reports a new chemical anti-phage defence system that is widespread in Streptomyces spp.

    • Ashley York
    In Brief
  • This month’s Under the Lens discusses electron cryotomography (ECT) as a powerful tool for investigating host–pathogen interactions.

    • Emeline Lawarée
    • Rafael Custódio
    Under the Lens
  • This study shows that in the non-growing, antibiotic-tolerant state, Salmonella enterica subsp. enterica serovar Typhimurium actively subverts host cells to promote survival during antibiotic exposure, persistent infections and long-term survival.

    • Andrea Du Toit
    In Brief
  • This study found that lactic-acid-producing bacteria support the expansion of intestinal stem cells and epithelial differentiation.

    • Andrea Du Toit
    In Brief
  • This study found that when filamentous actinomycetes are exposed to osmotic stress they extrude previously undetected cell wall-deficient cells, termed S-cells, that enable actinomycetes to thrive under hyperosmotic stress conditions.

    • Andrea Du Toit
    In Brief
  • This study investigates the phenotypic heterogeneity in influenza virus size and composition.

    • Ursula Hofer
    Research Highlight
  • This study reveals that a quorum-sensing molecule of Pseudomonas aeruginosa induces host immune cell death by causing cell surface lipid domain dissolution.

    • Ashley York
    In Brief
  • This study identifies an emergent phenotype that enables Escherichia coli to escape near-lethal concentrations of antibiotics.

    • Ashley York
    In Brief
  • This month’s Genome Watch highlights how next-generation sequencing technologies provide crucial information during disease outbreaks and thus inform the public health response.

    • Sandra Van Puyvelde
    • Silvia Argimon
    Genome Watch
  • This study uncovers a strategy whereby pandemic methicillin-resistant S. aureus clones subvert antibody-mediated immunity.

    • Andrea Du Toit
    Research Highlight
  • Two recent studies identify factors that accelerate the rate of antimicrobial resistance development.

    • Ashley York
    Research Highlight
  • This study reports the experimental evolution of the opportunistic fungal pathogen Candida albicans into a non-pathogenic commensal that provides resistance against other pathogens.

    • Ashley York
    Research Highlight
  • A new report shows that investing in the prevention of antimicrobial resistance now will have a big pay-off in the future.

    • Ursula Hofer
    Research Highlight
  • This study reveals a novel mechanism of receptor-triggered toxin delivery.

    • Andrea Du Toit
    Research Highlight
  • Recently emerged enteroviruses have been linked to acute paralysis, and a new study now shows that these viruses have developed neurotropism.

    • Ursula Hofer
    Research Highlight