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A recent study found that the Helicobacter pylori genome evolves during disease progression and that these genomic changes select for effective colonizers of gastric metaplasia.
A recent study reports the development of a biomarker-responsive engineered bacterium that can diagnose, record and treat inflammatory bowel disease in mice.
Xie et al. show that the harmaline metabolite produced by Akkermansia muciniphila modulates nuclear factor-κB signalling and reduces severe fever with thrombocytopenia syndrome severity.
This Genome Watch explores how metagenomics aids in profiling plant-derived microorganisms and molecules that could have an impact on the composition and function of the human gut microbiome.
Thaiss and colleagues report a gut–brain connection in mice that regulates the motivation for exercise, linking the intestinal microbiome to midbrain dopamine signalling.