News & Comment

The study reveals how a satellite phage-encoded protein directs the assembly of coat proteins into small capsids.

In this study, Tsuji et al. report the glycolipid 7DW8-5 that exploits the host innate immune system to control SARS-CoV-2, respiratory syncytial virus and influenza virus infections.

The authors developed a refillable, long-acting subcutaneous nanofluidic antiretroviral delivery implant that conferred protection against infection with simian–human immunodeficiency virus in rhesus macaques.

In this study, Douglas et al. examine the role of the staphylococcal TcaA protein in human serum susceptibility during bacteraemia.

In this study, Irazoki et al. show that Vibrio cholerae releases d-amino acids into the environment, which are sensed by a bacterial chemoreceptor to prompt a repellent chemotactic response.

This study provides insights into the mechanism whereby Citrobacter rodentium transitions from the intestinal lumen to its mucosal niche.

This Genome Watch highlights new computational approaches aimed at circumventing contamination in low-biomass microbiome studies.

This study reports that human BTN3A3 restricts replication of avian influenza A viruses (IAVs) but not human IAVs, and that BTN3A3 evasion promotes spillover into humans.

This study suggests that pre-existing DENV immunity has a negative effect on the pathogenesis of secondary ZIKV infection during pregnancy in marmosets.

This study reveals the conformational changes of the utilisome that facilitate glycan processing and import.

This study reports that an engineered bee symbiont provides protection against Nosema ceranae infection.

The human microbiome has a crucial role in global health, with implications for achieving the Sustainable Development Goals (SDGs). Understanding and harnessing the potential of the microbiome, while recognizing its link to the global ecosystem, can drive innovative strategies for improved public health, and promote sustainable development.

African microbiomes are much neglected and previous studies have disproportionately focused on the Global North. Africa harbours substantial genetic diversity in terms of its ecosystems, humans and animals. In this Comment, we highlight the lack of information regarding microbiome datasets from Africa and propose mechanisms for increasing microbiome research in Africa.

In this study, Fidelle et al. show that recolonization of the gut by Enterocloster spp. after antibiotic treatment compromises the anticancer effect of immune checkpoint inhibitor therapy.

In this study, Catchpole et al. identify the first self-transmissible conjugative plasmid in the euryarchaeon Thermococcus sp. 33-3 and use it to genetically modify diverse hyperthermophilic archaea.

In this study, Vidakovic et al. show that during infection Vibrio cholerae forms biofilms on the surface of human immune cells to kill them and then disperses.

This study shows that healthy individuals are reservoirs for genotypically and phenotypically diverse Candida albicans strains that retain their capacity to cause disease.

This Genome Watch highlights the recent developments of prokaryotic nomenclature leading to the coexistence of two parallel prokaryotic nomenclatural codes.

In this study, Liu et al. demonstrate that the T7SS of the rhizobacterium Bacillus velezensis SQR9 and its effector protein YukE cause iron leakage in plant roots to support root colonization.

This study shows that substrate stiffness has an impact on early microcolony formation.