News & Comment

A recent study by Florezet al. shows a direct correlation between the export of PQS and OMV biogenesis, which suggests that by modulating the export of PQS it is possible to regulate the production of OMVs.

Two recent studies shed light on the mechanisms that coordinate cell division with chromosomal replication and segregation in two distinct bacterial species.

A recent study provides a mechanism by which a bacteriophage may increase the translocation ofNeisseria meningitidisinto the bloodstream.

This month's Genome Watch discusses how genome-wide epistasis analysis and genome-to-genome analyses are providing insights into the relevance of interactions between and within genomes of pathogens and their hosts.

Two new studies explore the effect of overexpression of efflux pumps on bacterial fitness as well as the effect of loss of efflux function on virulence.

Two independent recent studies have revealed how distinct components of the biofilm matrix contribute to its architectural stability and functionality.

Two recent studies provide new insights into the fusion stage of HIV-1 entry.

In this study, Patel, Whiteet al. discover that the hepatitis B virus pre-genome RNA contains specific nucleotide motifs that mediate interactions with the viral capsid protein to drive nucleocapsid assembly.

This study presents cryo-electron microscopy structures of the type I-E Cascade and provides insights into PAM-dependent R-loop formation, Cas3 recruitment and substrate handover.

This month's Genome Watch highlights how sequencing the genomes of multiple bacterial isolates from humans and animal infection models has revealed the presence of mutations that might represent adaptations for persistence in the host.

This study found a new role for chaperone–usher pathway (CUP) pili in the colonization of the gut by uropathogenicEscherichia coli(UPEC) and identified a mannoside compound that could be used to prevent their binding to host cells.