News & Comment

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  • Global COVID-19 vaccine equity remains aspirational for much of the world. But the emergence of rapidly evolving SARS-CoV-2 variants provides new opportunities to correct past public policies, support local vaccine production and combat rising anti-vaccine aggression.

    • Peter J. Hotez
    Comment
  • This study provides insights into how to determine how mimiviruses package and protect their genomes.

    • Andrea Du Toit
    In Brief
  • Two new studies report comprehensive analyses of the fungal communities associated with cancer.

    • Andrea Du Toit
    In Brief
  • This Genome Watch article highlights how single-cell sequencing has transformed the approaches to understand schistosome developmental biology.

    • Gabriel Rinaldi
    • Teresa Attenborough
    • Matt Berriman
    Genome Watch
  • A recent study finds that an enzyme expressed by gut bacteria can inactivate anti-cancer fluoropyrimidine drugs, reducing drug efficacy and bioavailability in mice.

    • Michael Attwaters
    Research Highlight
  • This study found that the SARS-CoV-2 protein ORF8 disrupts host epigenetic regulation through histone mimicry.

    • Ashley York
    In Brief
  • A recent study investigated viral loads in clinical samples with the aim of understanding the distribution of monkeypox virus in the human body and how this distribution may be influencing viral transmission

    • Ashley York
    In Brief
  • Phage–antibiotic combination therapy was successful in treating extensively-resistant Pseudomonas aeruginosa infection following liver transplantation in a toddler.

    • Ashley York
    In Brief
  • A recent study characterizes an inducible morphotype of Cryptococcus neoformans that is critical for extrapulmonary organ entry.

    • Agustina Taglialegna
    Research Highlight
  • Two studies report how soil microbiota adapts after wildfires and soil warming.

    • Lucia Brunello
    Research Highlight
  • This study reports viral transmission between two phytopathogenic species that have similar ecological niches on oilseed rape.

    • Andrea Du Toit
    In Brief
  • This study provides novel insights into the architecture of the cell division site and the dynamics of septal peptidoglycan biogenesis.

    • Andrea Du Toit
    In Brief
  • This study describes a novel parasitic interaction between bacteria and archaea.

    • Andrea Du Toit
    In Brief
  • The biofilm community has historically been very successful in aggregating scientists from very diverse fields. Now, we must harness innovative technologies across disciplines to illuminate the biofilm microenvironment and create in vitro models that accurately recapitulate natural environments.

    • Kendra P. Rumbaugh
    Comment
  • A study in a nematode model of digestion finds that a gut commensal activates digestion by modulating host innate immunity.

    • Grant Otto
    In Brief
  • This study comprehensively assesses the fitness cost of mutations conferring resistance to an antifungal drug, revealing a steep resistance–function trade-off.

    • Grant Otto
    In Brief
  • This study reports that dietary sugar induces changes in the intestinal microbiota that disrupt immune-mediated protection from metabolic syndrome in mice.

    • Andrea Du Toit
    Research Highlight
  • A recent study reports the targeted suppression of an inflammatory bowel disease-associated pathobiont by phage therapy for treatment of intestinal inflammation.

    • Ashley York
    Research Highlight