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A recent study investigated the structural dynamics of a matrix protein ofVibrio choleraebiofilms and examined how this protein modulates the architecture of the biofilm.
In a recent study, Takataet al. show that viral CG suppression is key for the replication of HIV-1 and that the zinc-finger antiviral protein (ZAP), by specifically binding to CG-rich RNA sequences, can identify non-self RNAs and target them for degradation.
An improved understanding of the origins and spread of drug-resistant bacteria, as well as the identification of novel antimicrobial compounds and new drug combinations, will facilitate the development of better dosing regimens and novel strategies to manage drug resistance and prevent the dissemination of resistant bacteria.
This study reveals a two-component response regulator system in enterotoxigenicBacteroides fragilis strains that regulates the expression of the colitis-inducing B. fragilistoxin.
This month's Genome Watch examines how coupling deep sequencing of the gut microbiome with metabolic profiles can advance the development of microbiota-focused personalized precision nutrition.
A recent study by Silvesteret al. found that a conserved quorum sensing signalling pathway regulates interspecies crosstalk in trypanosome co-infections and provided novel insights into trypanosome virulence and transmission.
A recent study identified a host-derived ammonium transporter in the genome of an algal virus that increases the rate of nitrogen uptake by infected cells and changes how the host accesses diverse nitrogen sources during infection.
This study reports thatLegionella pneumophilaregulates mitochondrial dynamics to subvert mitochondrial bioenergetics of infected cells in a process that involves a bacterial T4SS effector and a host fission protein.
A recent study describes a new molecular mechanism used by the gut microbiota to maintain a state of homeostasis in the intestinal lumen, and highlights the importance of PPARγ signalling in this complex regulation.
A recent study investigated how the history of adaptation to a single antibiotic influences the trajectory of evolutionary dynamics during subsequent treatments with different antibiotics.
This month's Genome Watch discusses the release of 1,003 bacterial and archaeal genomes, and describes how they could increase our understanding of the diversity of microbial biological functions and contribute to improved metagenomic analyses.