Articles in 2019

This study used a large-scale metagenomic-assembly approach and uncovered thousands of new species associated with the human microbiome.

In a recent study, researchers examined the super-donor phenomenon in faecal microbiota transplantation (FMT) and concluded that the existence of FMT super-donors is not yet supported, and they suggest a more personalized approach could improve the success of FMT.

In a new study, Honda and colleagues identify a consortium of human gut microbiota that can boost the efficacy of anticancer immune therapy.

Two studies address the mechanism of phage induction in the context of a gut symbiont and enterohaemorrhagic Escherichia coli infection.

Combinations of antibiotics and of antibiotics with non-antibiotic activity-enhancing compounds offer a productive strategy to address the widespread emergence of antibiotic-resistant strains. In this Review, Tyers and Wright outline a theoretical and practical framework for the development of effective drug combinations.

A recent study shows that silencing of the type VI secretion system is essential for plasmid conjugation and the dissemination of multidrug resistance in Acinetobacter baumannii.

Methane metabolism has a central role in the global carbon cycle. In the Review, Tyson and colleagues discuss the enzymatic pathways responsible for archaeal methane metabolism and highlight the evolutionary relationships of key enzymes with recently discovered alkane-oxidizing archaea.

This month’s Genome Watch explores the genetic variability of the anti-malaria vaccine protein and discusses its significance for an efficacious intervention.

Previously, Zika virus was thought to cause mild infection, and serious complications only recently emerged. Liu, Shi and Qin discuss how the virus has evolved during its recent global spread and consider how these changes might be linked to pathogenesis.

A recent study reports a model for Pseudomonas aeruginosa surface colonization that creates phenotypic diversity to enhance spread and virulence.