News & Comment

Neutrophils support the spread of breast cancer cells to the lungs through the production of leukotrienes.

Group 2 innate lymphoid cells drive memory T helper 2 cell responses by licensing dendritic cells.

Tracking of human memory T cells infused after haematopoietic stem cell transplantation indicates that long-term persistent memory T cells originate mainly from stem cell memory T cells and are favoured by antigen rechallenge.

The guanine nucleotide exchange factor DENND1B specifically regulates TCR signalling in T_H2 cells and protects against allergy.

Fabienne Mackay describes a 2011 paper by Wineret al. that observed an effect of diet on the B cell repertoire.

A rare population of neuroendocrine cells in the lung epithelium can shape immune responses and tissue remodelling in the lungs.

Memory B cells are produced early, whereas long-lived plasma cells are produced late, in the germinal centre response.

Downregulation of the T-box transcription factors eomesodermin (EOMES) and T-bet drives tissue-resident memory T cell fate.

Peter Doherty describes the 1962 paper by Jim Gowans that characterized lymphocyte-mediated immunity.

Decreased cholesterol metabolism in response to virus infection potentiates the type I interferon-mediated antiviral response.